US: 31-year-old forced to get nose removed, severe fungal infection to be blamed

Florida-based Brandon Boothby had to undergo removal of his nose due to a severe fungal infection.

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Edited By: Sonia Dham
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In a harrowing tale of medical adversity, a 31-year-old man from Florida, Brandon Boothby, found himself compelled to undergo the removal of his nose due to a severe fungal infection. This uncommon medical condition was exacerbated by a rare autoimmune disorder, leading to a cascade of life-threatening complications.

In a two-in-a-million condition, Brandon Boothby's ordeal began with flu-like symptoms, progressively worsening until he reached a state of weakness that caused him to faint. Hospital tests revealed a diagnosis of severe aplastic anemia, an autoimmune condition where the body fails to produce sufficient new blood cells. This left Boothby highly vulnerable to serious infections.

Escalation to a fungal nightmare

Amidst the challenges of aplastic anemia, Boothby encountered a fungal infection in his nose that started devouring his flesh. The situation became critical as the infection neared his brain and eyes, prompting a dire decision—to remove his nose to prevent the life-threatening progression.

Boothby recounts, "It wasn't hard to breathe when my nose got infected; it was just the local pain and swelling that was alarming." Five surgeries were performed in a desperate attempt to halt the invasive fungus that posed a direct threat to his life.

The surgical intervention

Two weeks into the battle against the fungal infection, doctors faced a critical choice—remove the nose and part of the eye socket to save Boothby's life. This drastic measure was necessary to prevent the fungus from advancing further, potentially reaching the brain. Following the surgery, a prosthetic nose was fitted for the 31-year-old.

Graft versus host syndrome

Boothby's challenges did not end with the surgical intervention. Post a bone marrow transplant, he developed graft versus host syndrome, a condition where newly produced healthy blood cells attacked his own body. This led to severe malnourishment, eczema-like symptoms, and organ inflammation, posing a risk of intestinal removal.

Remarkably, due to his fitness before the complications, doctors opted for a natural healing approach. 

Boothby's resilience prevailed, and he gradually overcame the syndrome. He now shares his story, emphasizing the importance of awareness about rare conditions and the significance of organ donation.

What’s next?

As Boothby continues his journey to complete recovery, he remains optimistic, acknowledging the support of healthcare professionals and his own determination. "They (doctors) told me it could take up to three years to heal completely, but it's been almost two now, and it's going extremely well," he shared.

Returning to full-time duty as a firefighter, Boothby appreciates life with a newfound perspective. "Now, I wake up with a whole different mindset. I appreciate everything, even if it's just standing outside and enjoying the weather or being with my daughter," he adds.