New Delhi: In a significant breakthrough for lung cancer treatment, the U.S. Food and Drug Administration (FDA) has approved Johnson & Johnsons (J&J) chemotherapy-free therapy for non-small cell lung cancer (NSCLC). The approval covers a combination of J&Js Rybrevant and lazertinib, now authorized as a first-line treatment for NSCLC patients with an EGFR mutation.This new combination therapy offers a novel alternative to AstraZenecas Tagrisso, the current standard treatment. Rybrevant and lazertinib have shown promising results in clinical trials by extending the time patients live without disease progression. This advancement provides hope for those affected by this aggressive cancer, offering them a more effective and less invasive treatment option.J&J on projecting issueThe approval is expected to be a game-changer in the oncology landscape. J&J is projecting that Rybrevant will achieve over $5 billion in peak sales, highlighting the companys confidence in the drugs commercial potential. The approval also reflects the ongoing efforts to introduce more personalized and targeted therapies for cancer, minimizing the need for traditional chemotherapy.J&Js success with Rybrevant underscores the growing shift towards precision medicine in the battle against cancer. With a rising demand for more effective and less toxic treatments, Rybrevant and lazertinib provide a much-needed option for NSCLC patients, offering better outcomes and improved quality of life.