COVID-19: Researchers identify rapid tests are effective for new variants

Researchers have been testing COVID-19 tests that were used by people earlier. Are they less or more effective for the new variant? Read Below to find out.

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Edited By: Shruti Chopra
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The efficacy of over 100 quick antigen test kits on over 300 variations was examined by the National Institutes of Health, through its Variant Task Force, using clinical samples collected from diagnostic labs across the United States between 2020 and 2023. Most of the kits were able to identify both previously known variations and new ones.

Our group of researchers has been studying the accuracy and performance of COVID-19 exams for the last few years. We recognize that concerns about the validity of these tests may persist among the general public, especially in light of the constant emergence of novel variations.

When do I test?

It is currently advised to hold off on taking a quick test for four to five days if you have been exposed to someone but are not exhibiting any symptoms.

 Wait two days and take another test if the results are negative.
Take a third test two additional days later if the results are still negative. This method works best for non-symptomatic COVID-19 infection detection.

Additionally, if you suspect you may have been exposed, it is advised that you get a quick test as soon as possible before visiting someone unwell.

How effective are the tests?

There are two main categories of testing used to identify SARS-CoV-2.
The first, known as an RT-PCR test, has a greater than 95% accuracy rate in identifying the virus. 

Earlier in the pandemic, drive-through and walk-in testing locations administered these tests to the majority of Americans.
Nowadays, most are performed in a doctor's office or clinic; however, some can be done at home using PCR tests, which are usually five to ten times more expensive than quick antigen testing.

The other kind is an antigen test, also referred to as a fast test and having an accuracy rate of above 80%. The majority of these tests are available at pharmacies and supermarkets over the counter. Rapid antigen tests can be used without prior training, are reasonably priced, and often yield findings in 10 to 15 minutes. 

One disadvantage is that their accuracy is lower than that of PCR testing, particularly in the early stages of an illness when the body contains less virus.

Research on COVID-19 tests 

Even though our original study was finished in January 2022, our team has shown that these tests perform as well in 2024 as they did earlier in the pandemic, when various strains were circulating, despite these inherent constraints. This is because, in contrast to other portions of the virus that have seen numerous changes over the past two years, the virus protein identified by antigen tests has not altered significantly. 

Similar findings were obtained from a different study that examined the fast antigen test's accuracy between 2020 and 2022. That being said, to find novel SARS-CoV-2 variations, scientists ensure that the tests are tested. They use labs and computer simulations to conduct these tests. During a COVID-19 testing trial, researchers gather samples beneath tents while donning masks and other protective gear.

What to do if you notice symptoms 

As soon as you notice any symptoms, do a quick test. You can be quite certain that you have the infection if your test results are positive. Test again after two days if the results are negative.

It takes a few days for the virus to accumulate to levels that the fast test can detect, which makes this waiting period crucial. According to recent studies, the omicron family of variants takes a little longer for this to happen than variants from a few years ago. Despite being exposed one may not feel sick.